Mediation Analysis With Matched Case-Control Study Designs
نویسندگان
چکیده
منابع مشابه
Why match? Investigating matched case-control study designs with causal effect estimation.
Matched case-control study designs are commonly implemented in the field of public health. While matching is intended to eliminate confounding, the main potential benefit of matching in case-control studies is a gain in efficiency. Methods for analyzing matched case-control studies have focused on utilizing conditional logistic regression models that provide conditional and not causal estimates...
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Background: several studies have explored the relationship between blood lipid levels and depressive disorders. Specific studies reported an association between lower serum cholesterol and depressive disorder, while some other studies no connection. The aim of this study was to evaluate the relationship of serum lipid profiles and serum serotonin with depressive disorder. Methods: In the prese...
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BACKGROUND Are applicants from private schools advantaged in gaining entry to degrees in medicine? This is of international significance and there is continuing research in a range of nations including the USA, the UK, other English-speaking nations and EU countries. Our purpose is to seek causal explanations using a quantitative approach. METHODS We took as a case study admission to medicine...
متن کاملA simulation study on matched case-control designs in the perspective of causal diagrams
BACKGROUND In observational studies, matched case-control designs are routinely conducted to improve study precision. How to select covariates for match or adjustment, however, is still a great challenge for estimating causal effect between the exposure E and outcome D. METHODS From the perspective of causal diagrams, 9 scenarios of causal relationships among exposure (E), outcome (D) and the...
متن کاملAnalysis of matched case-control studies.
There are two common misconceptions about case-control studies: that matching in itself eliminates (controls) confounding by the matching factors, and that if matching has been performed, then a “matched analysis” is required. However, matching in a case-control study does not control for confounding by the matching factors; in fact it can introduce confounding by the matching factors even when...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2016
ISSN: 0002-9262,1476-6256
DOI: 10.1093/aje/kww038